4XB2

Hyperthermophilic archaeal homoserine dehydrogenase mutant in complex with NADPH

Summary for 4XB2

Entry DOI	10.2210/pdb4xb2/pdb
Related	4XB1
Descriptor	319aa long hypothetical homoserine dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, L-HOMOSERINE, ... (5 entities in total)
Functional Keywords	rossmann fold, oxidoreductase
Biological source	Pyrococcus horikoshii OT3
Total number of polymer chains	2
Total formula weight	75608.85
Authors	Sakuraba, H.,Inoue, S.,Yoneda, K.,Ohshima, T. (deposition date: 2014-12-16, release date: 2015-07-15, Last modification date: 2023-11-15)
Primary citation	Hayashi, J.,Inoue, S.,Kim, K.,Yoneda, K.,Kawarabayasi, Y.,Ohshima, T.,Sakuraba, H. Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases. Sci Rep, 5:11674-11674, 2015 Cited by PubMed: 26154028 DOI: 10.1038/srep11674 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.43 Å)

Structure validation