4X9W
PLK-1 polo-box domain in complex with Bioactive Imidazolium-containing phosphopeptide macrocycle 4C
Summary for 4X9W
Entry DOI | 10.2210/pdb4x9w/pdb |
Related | 4X9R |
Descriptor | Serine/threonine-protein kinase PLK1, Macrocyclic phosphopeptide 4C (3 entities in total) |
Functional Keywords | transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: P53350 |
Total number of polymer chains | 2 |
Total formula weight | 28194.24 |
Authors | Grant, R.A.,Qian, W.-J.,Yaffe, M.B.,Burke, T.R. (deposition date: 2014-12-11, release date: 2015-07-29, Last modification date: 2023-11-15) |
Primary citation | Qian, W.J.,Park, J.E.,Grant, R.,Lai, C.C.,Kelley, J.A.,Yaffe, M.B.,Lee, K.S.,Burke, T.R. Neighbor-directed histidine N ( tau )-alkylation: A route to imidazolium-containing phosphopeptide macrocycles. Biopolymers, 104:663-673, 2015 Cited by PubMed: 26152807DOI: 10.1002/bip.22698 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.798 Å) |
Structure validation
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