4X9W
PLK-1 polo-box domain in complex with Bioactive Imidazolium-containing phosphopeptide macrocycle 4C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase PLK1 | polymer | 237 | 27285.2 | 1 | UniProt (P53350) Pfam (PF00659) In PDB | Homo sapiens (Human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
| 2 | B | Macrocyclic phosphopeptide 4C | polymer | 5 | 909.1 | 1 | synthetic construct | (4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol | |
| 3 | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence modifications
A: 371 - 603 (UniProt: P53350)
| PDB | External Database | Details |
|---|---|---|
| Gly 367 | - | expression tag |
| Ala 368 | - | expression tag |
| His 369 | - | expression tag |
| Met 370 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28194.2 | |
| All* | Total formula weight | 28194.2 |
