4X96

Low resolution crystal structure of Lecithin:Cholesterol Acyltransferase (LCAT; residues 21-397)

4X96 の概要

• エントリーDOI: 10.2210/pdb4x96/pdb
• 関連するPDBエントリー: 4X90 4X91 4X92 4X93 4X94 4X95 4X97
• 分子名称: Phosphatidylcholine-sterol acyltransferase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: hydrolase, phospholipase, esterase, acyltransferase, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 180340.08

構造登録者

Glukhova, A.,Tesmer, J.J.G. (登録日: 2014-12-11, 公開日: 2015-03-25, 最終更新日: 2023-09-27)

• 主引用文献: Glukhova, A.,Hinkovska-Galcheva, V.,Kelly, R.,Abe, A.,Shayman, J.A.,Tesmer, J.J.; Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase.; Nat Commun, 6:6250-6250, 2015; PubMed: 25727495; DOI: 10.1038/ncomms7250

実験手法

X-RAY DIFFRACTION (8.69 Å)