4X95
Crystal structure of fully glycosylated Lysosomal Phospholipase A2 in complex with methyl arachidonyl fluorophosphonate (MAFP)
Summary for 4X95
Entry DOI | 10.2210/pdb4x95/pdb |
Related | 4X90 4X91 4X92 4X93 4X94 4X96 4X97 |
Descriptor | Group XV phospholipase A2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | hydrolase, phospholipase, mafp, acyltransferase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 89483.35 |
Authors | Glukhova, A.,Tesmer, J.J.G. (deposition date: 2014-12-11, release date: 2015-03-25, Last modification date: 2023-09-27) |
Primary citation | Glukhova, A.,Hinkovska-Galcheva, V.,Kelly, R.,Abe, A.,Shayman, J.A.,Tesmer, J.J. Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6:6250-6250, 2015 Cited by PubMed: 25727495DOI: 10.1038/ncomms7250 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.08 Å) |
Structure validation
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