4X95
Crystal structure of fully glycosylated Lysosomal Phospholipase A2 in complex with methyl arachidonyl fluorophosphonate (MAFP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Group XV phospholipase A2 | polymer | 380 | 43121.0 | 2 | UniProt (Q8NCC3) Pfam (PF02450) | Homo sapiens (Human) | 1-O-acylceramide synthase,ACS,LCAT-like lysophospholipase,LLPL,Lysophospholipase 3,Lysosomal phospholipase A2,LPLA2 |
| 2 | C, D (C, D) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 3 | E, F, G, I, J... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 4 | H, L (A, B) | METHYL ARACHIDONYL FLUOROPHOSPHONATE | non-polymer | 370.5 | 2 | Chemie (MAY) |
Sequence modifications
A, B: 1 - 379 (UniProt: Q8NCC3)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86242.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1173.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2068.2 | |
| All* | Total formula weight | 89483.4 |
