4X7R

Crystal structure of S. aureus TarM G117R mutant in complex with Fondaparinux, alpha-GlcNAc-glycerol and UDP

4X7R の概要

• エントリーDOI: 10.2210/pdb4x7r/pdb
• 関連するPDBエントリー: 4X6L 4X7M 4X7P
• 関連するBIRD辞書のPRD_ID: PRD_900028
• 分子名称: TarM, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, URIDINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: glycosyltransferase gt-b retaining wall teichoic acid, transferase
• 由来する生物種: Staphylococcus aureus subsp. aureus 21178
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 119343.09

構造登録者

Worrall, L.J.,Sobhanifar, S.,Strynadka, N.C. (登録日: 2014-12-09, 公開日: 2015-02-25, 最終更新日: 2024-02-28)

• 主引用文献: Sobhanifar, S.,Worrall, L.J.,Gruninger, R.J.,Wasney, G.A.,Blaukopf, M.,Baumann, L.,Lameignere, E.,Solomonson, M.,Brown, E.D.,Withers, S.G.,Strynadka, N.C.; Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.; Proc.Natl.Acad.Sci.USA, 112:E576-E585, 2015; PubMed: 25624472; DOI: 10.1073/pnas.1418084112

実験手法

X-RAY DIFFRACTION (2.15 Å)