4X5E
Anthranilate phosphoribosyltransferase variant R194A from Mycobacterium tuberculosis with pyrophosphate, Mg2+ and anthranilate bound
Summary for 4X5E
Entry DOI | 10.2210/pdb4x5e/pdb |
Related | 4X58 4X59 4X5A 4X5B 4X5C 4X5D |
Descriptor | Anthranilate phosphoribosyltransferase, PYROPHOSPHATE 2-, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | anthranilate phosphoribosyltransferase, anthranilic acids, mycobacterium tuberculosis, magnesium, tryptophan, mutation, transferase, magnesium binding, phosphoribosyl pyrophosphate |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 78983.68 |
Authors | Cookson, T.V.M.,Evans, G.L.,Parker, E.J.,Lott, J.S. (deposition date: 2014-12-05, release date: 2015-11-25, Last modification date: 2023-11-15) |
Primary citation | Cookson, T.V.,Evans, G.L.,Castell, A.,Baker, E.N.,Lott, J.S.,Parker, E.J. Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site. Biochemistry, 54:6082-6092, 2015 Cited by PubMed: 26356348DOI: 10.1021/acs.biochem.5b00612 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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