4X5B
Anthranilate phosphoribosyltransferase variant R193L from Mycobacterium tuberculosis in complex with PRPP and Mg
4X5B の概要
エントリーDOI | 10.2210/pdb4x5b/pdb |
関連するPDBエントリー | 4X58 4X59 4X5A 4X5C 4X5D 4X5E |
分子名称 | Anthranilate phosphoribosyltransferase, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, ... (4 entities in total) |
機能のキーワード | anthranilate phosphoribosyltransferase, anthranilic acids, mycobacterium tuberculosis, magnesium, tryptophan, mutation, transferase, magnesium binding, phosphoribosyl pyrophosphate |
由来する生物種 | Mycobacterium tuberculosis |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 78438.45 |
構造登録者 | |
主引用文献 | Cookson, T.V.,Evans, G.L.,Castell, A.,Baker, E.N.,Lott, J.S.,Parker, E.J. Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site. Biochemistry, 54:6082-6092, 2015 Cited by PubMed: 26356348DOI: 10.1021/acs.biochem.5b00612 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.47 Å) |
構造検証レポート
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