4X4X
Retrofitting antibodies with stabilizing mutations. Herceptin scFv mutant.
Summary for 4X4X
Entry DOI | 10.2210/pdb4x4x/pdb |
Related | 4X4Y 4X4Z |
Descriptor | Human Variable Heavy Chain of Herceptin, Human Variable Light Chain of Herceptin (3 entities in total) |
Functional Keywords | antibody stabilization mutations, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 4 |
Total formula weight | 52600.02 |
Authors | Langley, D.B.,Roome, B.,Christ, D. (deposition date: 2014-12-04, release date: 2015-12-23, Last modification date: 2020-01-08) |
Primary citation | Langley, D.B.,Roome, B.,Christ, D. Retrofitting antibodies with stabilizing mutations To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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