4X3F
Crystal structure of the intracellular domain of the M. tuberculosis Ser/Thr kinase PknA
Summary for 4X3F
| Entry DOI | 10.2210/pdb4x3f/pdb |
| Descriptor | Serine/threonine-protein kinase PknA, ... (4 entities in total) |
| Functional Keywords | kinase, autoinhibition, phosphorylation, transferase |
| Biological source | Mycobacterium tuberculosis More |
| Cellular location | Cell membrane ; Single-pass membrane protein : P9WI83 P9WI83 P9WI83 |
| Total number of polymer chains | 3 |
| Total formula weight | 107813.63 |
| Authors | Wagner, T.,Wehenkel, A.,Alzari, P.M.,Bellinzoni, M. (deposition date: 2014-11-28, release date: 2015-01-21, Last modification date: 2024-01-10) |
| Primary citation | Wagner, T.,Alexandre, M.,Duran, R.,Barilone, N.,Wehenkel, A.,Alzari, P.M.,Bellinzoni, M. The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation. Proteins, 83:982-988, 2015 Cited by PubMed: 25586004DOI: 10.1002/prot.24754 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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