4X34

Crystal structure of the 53BP1 tandem tudor domain in complex with p53K381acK382me2

4X34 の概要

• エントリーDOI: 10.2210/pdb4x34/pdb
• 分子名称: Tumor suppressor p53-binding protein 1, THR-SER-ARG-HIS-ALY-MLY-LEU-MET-PHE-LYS (3 entities in total)
• 機能のキーワード: posttranslational modifications, tandem tudor domain of 53bp1, transcription-transcription inhibitor complex, transcription/transcription inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 29934.13

構造登録者

Tong, Q.,Kutateladze, T.G. (登録日: 2014-11-27, 公開日: 2015-03-04, 最終更新日: 2023-11-15)

• 主引用文献: Tong, Q.,Mazur, S.J.,Rincon-Arano, H.,Rothbart, S.B.,Kuznetsov, D.M.,Cui, G.,Liu, W.H.,Gete, Y.,Klein, B.J.,Jenkins, L.,Mer, G.,Kutateladze, A.G.,Strahl, B.D.,Groudine, M.,Appella, E.,Kutateladze, T.G.; An Acetyl-Methyl Switch Drives a Conformational Change in p53.; Structure, 23:322-331, 2015; PubMed: 25651062; DOI: 10.1016/j.str.2014.12.010

実験手法

X-RAY DIFFRACTION (1.801 Å)