4X2Y
Crystal structure of a chimeric Murine Norovirus NS6 protease (inactive C139A mutant) in which the P4-P4 prime residues of the cleavage junction in the extended C-terminus have been replaced by the corresponding residues from the NS2-3 junction.
Summary for 4X2Y
Entry DOI | 10.2210/pdb4x2y/pdb |
Related | 4ASH 4X2V 4X2W 4X2X |
Descriptor | NS6 Protease,NS6 Protease (2 entities in total) |
Functional Keywords | murine norovirus, protease, viral protein |
Biological source | Murine norovirus 1 More |
Total number of polymer chains | 2 |
Total formula weight | 37649.03 |
Authors | Leen, E.N.,Pfeil, M.-P.,Fernandes, H.,Curry, S. (deposition date: 2014-11-27, release date: 2015-02-18, Last modification date: 2024-01-10) |
Primary citation | Fernandes, H.,Leen, E.N.,Cromwell, H.,Pfeil, M.P.,Curry, S. Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions. Peerj, 3:e798-e798, 2015 Cited by PubMed: 25755927DOI: 10.7717/peerj.798 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.417 Å) |
Structure validation
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