4X2Y

Crystal structure of a chimeric Murine Norovirus NS6 protease (inactive C139A mutant) in which the P4-P4 prime residues of the cleavage junction in the extended C-terminus have been replaced by the corresponding residues from the NS2-3 junction.

4X2Y の概要

• エントリーDOI: 10.2210/pdb4x2y/pdb
• 関連するPDBエントリー: 4ASH 4X2V 4X2W 4X2X
• 分子名称: NS6 Protease,NS6 Protease (2 entities in total)
• 機能のキーワード: murine norovirus, protease, viral protein
• 由来する生物種: Murine norovirus 1; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37649.03

構造登録者

Leen, E.N.,Pfeil, M.-P.,Fernandes, H.,Curry, S. (登録日: 2014-11-27, 公開日: 2015-02-18, 最終更新日: 2024-01-10)

• 主引用文献: Fernandes, H.,Leen, E.N.,Cromwell, H.,Pfeil, M.P.,Curry, S.; Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions.; Peerj, 3:e798-e798, 2015; PubMed: 25755927; DOI: 10.7717/peerj.798

実験手法

X-RAY DIFFRACTION (2.417 Å)