4X0N

Porcine pancreatic alpha-amylase in complex with helianthamide, a novel proteinaceous inhibitor

4X0N の概要

• エントリーDOI: 10.2210/pdb4x0n/pdb
• 分子名称: Pancreatic alpha-amylase, Helianthamide, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: amylase, inhibitor, diabetes, protein inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Sus scrofa (Pig); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60236.67

構造登録者

Williams, L.K.,Brayer, G.D. (登録日: 2014-11-21, 公開日: 2015-11-25, 最終更新日: 2024-10-09)

• 主引用文献: Tysoe, C.,Williams, L.K.,Keyzers, R.,Nguyen, N.T.,Aguda, A.,Zhang, X.,Tarling, C.A.,Andersen, R.J.,Brayer, G.D.,Withers, S.G.; Structural Templating and Guided Refolding of the Potent Naturally Occurring Peptide Helianthamide Within the Active Site of Amylase, a Diabetes and Obesity Therapeutic Target; To Be Published,

実験手法

X-RAY DIFFRACTION (2.6001 Å)