4WZQ

Mutant K20E of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with RNA

Summary for 4WZQ

Entry DOI	10.2210/pdb4wzq/pdb
Related	1U09 1WNE
Descriptor	RNA dependent-RNA polymerase 3D, RNA template, RNAprimer, ... (5 entities in total)
Functional Keywords	rna dependent rna polymerase, nuclear localization signal, picornavirus, closed right-hand, transferase
Biological source	Foot-and-mouth disease virus More
Total number of polymer chains	3
Total formula weight	58986.23
Authors	Verdaguer, N.,Ferrer-Orta, C. (deposition date: 2014-11-20, release date: 2015-05-06, Last modification date: 2024-01-10)
Primary citation	Ferrer-Orta, C.,de la Higuera, I.,Caridi, F.,Sanchez-Aparicio, M.T.,Moreno, E.,Perales, C.,Singh, K.,Sarafianos, S.G.,Sobrino, F.,Domingo, E.,Verdaguer, N. Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. J.Virol., 89:6848-6859, 2015 Cited by PubMed: 25903341 DOI: 10.1128/JVI.03283-14 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation