4WQL

Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")-Ia, kanamycin-bound

4WQL の概要

• エントリーDOI: 10.2210/pdb4wql/pdb
• 関連するPDBエントリー: 4WQK
• 分子名称: 2''-aminoglycoside nucleotidyltransferase, MAGNESIUM ION, KANAMYCIN A, ... (6 entities in total)
• 機能のキーワード: antibiotic resistance, aminoglycosides, kanamycin, nucleotidylyltransferase, adenylyltransferase, nucleotidyltransferase fold, alpha/beta protein, structural genomics, center for structural genomics of infectious diseases, csgid, national institute of allergy and infectious diseases, niaid, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Klebsiella pneumoniae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21212.47

構造登録者

Cox, G.,Stogios, P.J.,Savchenko, A.,Wright, G.D.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2014-10-22, 公開日: 2014-11-12, 最終更新日: 2023-12-27)

• 主引用文献: Cox, G.,Stogios, P.J.,Savchenko, A.,Wright, G.D.; Structural and Molecular Basis for Resistance to Aminoglycoside Antibiotics by the Adenylyltransferase ANT(2)-Ia.; Mbio, 6:-, 2015; PubMed: 25564464; DOI: 10.1128/mBio.02180-14

実験手法

X-RAY DIFFRACTION (1.73 Å)