4WO0
Crystal structure of transthyretin in complex with apigenin
Summary for 4WO0
Entry DOI | 10.2210/pdb4wo0/pdb |
Related | 4WNJ 4WNS |
Descriptor | Transthyretin, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one (3 entities in total) |
Functional Keywords | transport protein, amyloidosis, negative cooperativity |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 28095.19 |
Authors | Zanotti, G.,Cianci, M.,Folli, C.,Berni, R. (deposition date: 2014-10-15, release date: 2015-08-05, Last modification date: 2024-01-10) |
Primary citation | Cianci, M.,Folli, C.,Zonta, F.,Florio, P.,Berni, R.,Zanotti, G. Structural evidence for asymmetric ligand binding to transthyretin. Acta Crystallogr.,Sect.D, 71:1582-1592, 2015 Cited by PubMed: 26249340DOI: 10.1107/S1399004715010585 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.339 Å) |
Structure validation
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