4WLW

CRYSTAL STRUCTURE OF THE AG(I) (ACTIVATOR) FORM OF E. COLI CUER, A COPPER EFFLUX REGULATOR, BOUND TO COPA PROMOTER DNA

Summary for 4WLW

• Entry DOI: 10.2210/pdb4wlw/pdb
• Related: 4WLS
• Descriptor: HTH-type transcriptional regulator CueR, DNA NON-TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP *DTP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DGP*DCP*DTP*DGP*DGP*DAP *DAP*DGP*DGP*DTP*DC)-3, DNA TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP*DTP *DTP*DCP*DCP*DAP*DGP*DCP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DAP *DGP*DGP*DTP*DC)-3, ... (4 entities in total)
• Functional Keywords: protein-dna complex, merr-family transcription regulator, ag(i)form, activator, transcription, transcription-dna complex, transcription/dna
• Biological source: Escherichia coli; More
• Total number of polymer chains: 3
• Total formula weight: 29628.83

Authors

Philips, S.J.,Canalizo-Hernandez, M.,Mondragon, A.,O'Halloran, T.V. (deposition date: 2014-10-08, release date: 2015-09-02, Last modification date: 2023-11-15)

• Primary citation: Philips, S.J.,Canalizo-Hernandez, M.,Yildirim, I.,Schatz, G.C.,Mondragon, A.,O'Halloran, T.V.; TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter.; Science, 349:877-881, 2015; PubMed: 26293965; DOI: 10.1126/science.aaa9809

Experimental method

X-RAY DIFFRACTION (2.8 Å)