4WLW

CRYSTAL STRUCTURE OF THE AG(I) (ACTIVATOR) FORM OF E. COLI CUER, A COPPER EFFLUX REGULATOR, BOUND TO COPA PROMOTER DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
A	0001216	molecular_function	DNA-binding transcription activator activity
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005507	molecular_function	copper ion binding
A	0005737	cellular_component	cytoplasm
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0032993	cellular_component	protein-DNA complex
A	0042802	molecular_function	identical protein binding
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue AG A 200

Chain	Residue
A	SER77
A	CYS112
A	CYS120
A	ILE122

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Functional Information from PROSITE/UniProt

site_id	PS00552
Number of Residues	23
Details	HTH_MERR_1 MerR-type HTH domain signature. SdVAkiTGLTskaIRfYEek.GLV

Chain	Residue	Details
A	SER4-VAL26

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	19
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00254

Chain	Residue	Details
A	SER4-LYS23

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING:

Chain	Residue	Details
A	CYS112
A	CYS120

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