4WKQ
1.85 angstrom structure of EGFR kinase domain with gefitinib
Summary for 4WKQ
Entry DOI | 10.2210/pdb4wkq/pdb |
Related | 2ITY |
Descriptor | Epidermal growth factor receptor, Gefitinib, SODIUM ION, ... (5 entities in total) |
Functional Keywords | inhibitor, complex, kinase, epidermal growth factor receptor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P00533 |
Total number of polymer chains | 1 |
Total formula weight | 38244.59 |
Authors | Yosaatmadja, Y.,Squire, C.J. (deposition date: 2014-10-03, release date: 2014-11-05, Last modification date: 2024-03-27) |
Primary citation | Yosaatmadja, Y.,Squire, C.J.,McKeage, M.,Flanagan, J.U. 1.85 angstrom structure of EGFR kinase domain with gefitinib To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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