4WHY
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P21 crystal form
Summary for 4WHY
Entry DOI | 10.2210/pdb4why/pdb |
Related | 4WHT |
Descriptor | epitope peptide, Heavy chain of Fab fragment derived from neutralizing antibody 3/11, Light chain of Fab fragment derived from neutralizing antibody 3/11, ... (4 entities in total) |
Functional Keywords | neutralizing epitope, envelope glycoprotein, e2, receptor-binding, viral protein |
Biological source | Rattus norvegicus (Norway Rat) More |
Total number of polymer chains | 12 |
Total formula weight | 208747.34 |
Authors | |
Primary citation | Meola, A.,Tarr, A.W.,England, P.,Meredith, L.W.,McClure, C.P.,Foung, S.K.,McKeating, J.A.,Ball, J.K.,Rey, F.A.,Krey, T. Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein e2 recognized by broadly neutralizing antibodies. J.Virol., 89:2170-2181, 2015 Cited by PubMed: 25473061DOI: 10.1128/JVI.02190-14 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.62 Å) |
Structure validation
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