4W5A

Complex structure of ATRX ADD bound to H3K9me3S10ph peptide

Summary for 4W5A

• Entry DOI: 10.2210/pdb4w5a/pdb
• Related: 3QL9 3QLA 3QLC 3QLN
• Descriptor: Transcriptional regulator ATRX, Peptide from Histone H3.3, ZINC ION, ... (4 entities in total)
• Functional Keywords: epigenetic regulation, complex, transcription, mitosis, hydrolase-structural protein complex, hydrolase/structural protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: P46100 P84243
• Total number of polymer chains: 6
• Total formula weight: 50033.86

Authors

Zhao, D.,Xiang, B.,Li, H. (deposition date: 2014-08-17, release date: 2015-01-21, Last modification date: 2023-11-08)

• Primary citation: Noh, K.M.,Maze, I.,Zhao, D.,Xiang, B.,Wenderski, W.,Lewis, P.W.,Shen, L.,Li, H.,Allis, C.D.; ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons; Proc.Natl.Acad.Sci.USA, 112:6820-6827, 2015; PubMed: 25538301; DOI: 10.1073/pnas.1411258112

Experimental method

X-RAY DIFFRACTION (2.6 Å)