4W4T

The crystal structure of the terminal R domain from the myxalamid PKS-NRPS biosynthetic pathway

Summary for 4W4T

Entry DOI	10.2210/pdb4w4t/pdb
Related	4U7W
Descriptor	MxaA, ACETATE ION (3 entities in total)
Functional Keywords	reductase, thioesterase, rossmann fold, polyketide, non-ribosomal peptide, polyketide synthase, non-ribosomal peptide synthetase, short-chain dehydrogenases, oxidoreductase
Biological source	Stigmatella aurantiaca
Total number of polymer chains	2
Total formula weight	93246.92
Authors	Tsai, S.C.,Keasling, J.D.,Luo, R.,Barajas, J.F.,Phelan, R.M.,Schaub, A.J.,Kliewer, J. (deposition date: 2014-08-15, release date: 2015-08-12, Last modification date: 2024-04-03)
Primary citation	Barajas, J.F.,Phelan, R.M.,Schaub, A.J.,Kliewer, J.T.,Kelly, P.J.,Jackson, D.R.,Luo, R.,Keasling, J.D.,Tsai, S.C. Comprehensive Structural and Biochemical Analysis of the Terminal Myxalamid Reductase Domain for the Engineered Production of Primary Alcohols. Chem.Biol., 22:1018-1029, 2015 Cited by PubMed: 26235055 DOI: 10.1016/j.chembiol.2015.06.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.845 Å)

Structure validation