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4V6I

Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome

This is a non-PDB format compatible entry.
Replaces:  3IZC
Summary for 4V6I
Entry DOI10.2210/pdb4v6i/pdb
Related3IZ5 3IZ6 3IZ7 3IZ9 3IZD
EMDB information1667 1669 1811
Descriptor40S ribosomal protein RACK1 (RACK1), 40S ribosomal protein rpS16 (S9p), 40S ribosomal protein rpS20 (S10p), ... (83 entities in total)
Functional Keywordseukaryotic ribosome, homology modeling, de novo modeling, ribosomal proteins, novel ribosomal proteins, ribosome
Biological sourceSaccharomyces cerevisiae (yeast)
More
Total number of polymer chains86
Total formula weight3104129.58
Authors
Primary citationArmache, J.P.,Jarasch, A.,Anger, A.M.,Villa, E.,Becker, T.,Bhushan, S.,Jossinet, F.,Habeck, M.,Dindar, G.,Franckenberg, S.,Marquez, V.,Mielke, T.,Thomm, M.,Berninghausen, O.,Beatrix, B.,Soding, J.,Westhof, E.,Wilson, D.N.,Beckmann, R.
Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107:19748-19753, 2010
Cited by
PubMed Abstract: Protein biosynthesis, the translation of the genetic code into polypeptides, occurs on ribonucleoprotein particles called ribosomes. Although X-ray structures of bacterial ribosomes are available, high-resolution structures of eukaryotic 80S ribosomes are lacking. Using cryoelectron microscopy and single-particle reconstruction, we have determined the structure of a translating plant (Triticum aestivum) 80S ribosome at 5.5-Å resolution. This map, together with a 6.1-Å map of a Saccharomyces cerevisiae 80S ribosome, has enabled us to model ∼98% of the rRNA. Accurate assignment of the rRNA expansion segments (ES) and variable regions has revealed unique ES-ES and r-protein-ES interactions, providing insight into the structure and evolution of the eukaryotic ribosome.
PubMed: 20980660
DOI: 10.1073/pnas.1009999107
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (8.8 Å)
Structure validation

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数据于2025-07-09公开中

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