Structure of a mammalian 80S ribosome obtained by docking homology models of the RNA and proteins into an 8.7 A cryo-EM map

This is a large structure.

Summary for 4V5Z

Integrates2ZKQ 2ZKR
EMDB information1480
Descriptor18S Ribosomal RNA, RNA Expansion segment ES3, RNA Expansion segment ES4, ... (86 entities in total)
Functional Keywordsprotein-rna complex, 40s ribosomal subunit, ribosomal protein-rna complex, ribosomal protein/rna
Biological sourceCanis familiaris (dog)
Total number of polymer chains86
Total molecular weight2902274.52
Chandramouli, P.,Akey, C.W. (deposition date: 2008-03-27, release date: 2014-07-09, Last modification date: 2015-03-25)
Primary citation
Chandramouli, P.,Topf, M.,Menetret, J.F.,Eswar, N.,Cannone, J.J.,Gutell, R.R.,Sali, A.,Akey, C.W.
Structure of the Mammalian 80S Ribosome at 8.7 A Resolution
Structure, 16:535-548, 2008
PubMed: 18400176 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2008.01.007
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone803.1%5.5%0.00MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 4v5z
no rotation
Molmil generated image of 4v5z
rotated about x axis by 90°
Molmil generated image of 4v5z
rotated about y axis by 90°