4V3D

The CIDRa domain from HB3var03 PfEMP1 bound to endothelial protein C receptor

Summary for 4V3D

Entry DOI	10.2210/pdb4v3d/pdb
Related	4V3E
Descriptor	HB3VAR03 CIDRA DOMAIN, ENDOTHELIAL PROTEIN C RECEPTOR, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	signaling protein, pfemp1, epcr, malaria, cidr domain, endothelial protein c receptor
Biological source	PLASMODIUM FALCIPARUM More
Total number of polymer chains	4
Total formula weight	102888.75
Authors	Lau, C.K.Y.,Turner, L.,Jespersen, J.S.,Lowe, E.D.,Petersen, B.,Wang, C.W.,Petersen, J.E.V.,Lusingu, J.,Theander, T.G.,Lavstsen, T.,Higgins, M.K. (deposition date: 2014-10-17, release date: 2014-12-17, Last modification date: 2024-01-10)
Primary citation	Lau, C.K.Y.,Turner, L.,Jespersen, J.S.,Lowe, E.D.,Petersen, B.,Wang, C.W.,Petersen, J.E.V.,Lusingu, J.,Theander, T.G.,Lavstsen, T.,Higgins, M.K. Structural Conservation Despite Huge Sequence Diversity Allows Epcr Binding by the Pfemp1 Family Implicated in Severe Childhood Malaria. Cell Host Microbe., 17:118-, 2015 Cited by PubMed: 25482433 DOI: 10.1016/J.CHOM.2014.11.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation