4V1F

Crystal structure of a mycobacterial ATP synthase rotor ring in complex with Bedaquiline

Summary for 4V1F

Related4V1G 4V1H
DescriptorF0F1 ATP SYNTHASE SUBUNIT C, Bedaquiline, B-OCTYLGLUCOSIDE, ... (4 entities in total)
Functional Keywordshydrolase, f1fo-atp synthase rotor membrane protein structure, drug binding and inhibition
Biological sourceMYCOBACTERIUM PHLEI
Total number of polymer chains3
Total molecular weight28964.39
Authors
Preiss, L.,Yildiz, O.,Meier, T. (deposition date: 2014-09-26, release date: 2015-05-20, Last modification date: 2019-01-16)
Primary citation
Preiss, L.,Langer, J.D.,Yildiz, O.,Eckhardt-Strelau, L.,Guillemont, J.E.,Koul, A.,Meier, T.
Structure of the mycobacterial ATP synthase Fo rotor ring in complex with the anti-TB drug bedaquiline.
Sci Adv, 1:e1500106-e1500106, 2015
PubMed: 26601184 (PDB entries with the same primary citation)
DOI: 10.1126/sciadv.1500106
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.697 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1644 0.4% 3.6% 4.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution