4UUU

1.7 A resolution structure of human cystathionine beta-synthase regulatory domain (del 516-525) in complex with SAM

4UUU の概要

• エントリーDOI: 10.2210/pdb4uuu/pdb
• 分子名称: CYSTATHIONINE BETA-SYNTHASE, S-ADENOSYLMETHIONINE, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: lyase
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Cytoplasm : P35520
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36436.01

構造登録者

Kopec, J.,McCorvie, T.J.,Fitzpatrick, F.,Strain-Damerell, C.,Froese, D.S.,Tallant, C.,Burgess-Brown, N.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Yue, W.W. (登録日: 2014-07-31, 公開日: 2014-08-13, 最終更新日: 2024-05-08)

• 主引用文献: Mccorvie, T.J.,Kopec, J.,Hyung, S.,Fitzpatrick, F.,Feng, X.,Termine, D.,Strain-Damerell, C.,Vollmar, M.,Fleming, J.,Janz, J.M.,Bulawa, C.,Yue, W.W.; Inter-Domain Communication of Human Cystathionine Beta Synthase: Structural Basis of S-Adenosyl-L-Methionine Activation.; J.Biol.Chem., 289:36018-, 2014; PubMed: 25336647; DOI: 10.1074/JBC.M114.610782

実験手法

X-RAY DIFFRACTION (1.71 Å)