4UTU

Structural and biochemical characterization of the N- acetylmannosamine-6-phosphate 2-epimerase from Clostridium perfringens

4UTU の概要

• エントリーDOI: 10.2210/pdb4utu/pdb
• 関連するPDBエントリー: 4UTT 4UTW
• 分子名称: N-ACETYLMANNOSAMINE-6-PHOSPHATE 2-EPIMERASE, N-acetylmannosamine-6-phosphate, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: isomerase, sugar 2-epimerase, sialic acid, sugar phosphate, enzyme mechanism, carbohydrate, mutagenesis, 1h nmr spectroscopy
• 由来する生物種: CLOSTRIDIUM PERFRINGENS STR. 13
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 50784.74

構造登録者

Pelissier, M.C.,Sebban-Kreuzer, C.,Guerlesquin, F.,Brannigan, J.A.,Davies, G.J.,Bourne, Y.,Vincent, F. (登録日: 2014-07-23, 公開日: 2014-10-15, 最終更新日: 2024-01-10)

• 主引用文献: Pelissier, M.C.,Sebban-Kreuzer, C.,Guerlesquin, F.,Brannigan, J.A.,Davies, G.J.,Bourne, Y.,Vincent, F.; Structural and Functional Characterization of the Clostridium Perfringens N-Acetylmannosamine-6-Phosphate 2-Epimerase Essential for the Sialic Acid Salvage Pathway; J.Biol.Chem., 289:35215-, 2014; PubMed: 25320079; DOI: 10.1074/JBC.M114.604272

実験手法

X-RAY DIFFRACTION (1.45 Å)