4UTU

Structural and biochemical characterization of the N- acetylmannosamine-6-phosphate 2-epimerase from Clostridium perfringens

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0006051	biological_process	N-acetylmannosamine metabolic process
A	0006053	biological_process	N-acetylmannosamine catabolic process
A	0009385	molecular_function	N-acylmannosamine-6-phosphate 2-epimerase activity
A	0016853	molecular_function	isomerase activity
A	0016857	molecular_function	racemase and epimerase activity, acting on carbohydrates and derivatives
A	0019262	biological_process	N-acetylneuraminate catabolic process
A	0047465	molecular_function	N-acylglucosamine-6-phosphate 2-epimerase activity
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0006051	biological_process	N-acetylmannosamine metabolic process
B	0006053	biological_process	N-acetylmannosamine catabolic process
B	0009385	molecular_function	N-acylmannosamine-6-phosphate 2-epimerase activity
B	0016853	molecular_function	isomerase activity
B	0016857	molecular_function	racemase and epimerase activity, acting on carbohydrates and derivatives
B	0019262	biological_process	N-acetylneuraminate catabolic process
B	0047465	molecular_function	N-acylglucosamine-6-phosphate 2-epimerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE LRY A 301

Chain	Residue
A	GLN14
A	GLY204
A	ARG208
A	HOH2055
A	HOH2058
A	HOH2198
A	HOH2202
A	HOH2235
A	HOH2236
A	HOH2256
A	HOH2261
A	ARG43
A	HOH2274
A	HOH2275
A	TYR75
A	THR147
A	TYR151
A	GLU180
A	GLY181
A	ARG182
A	GLY203

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site_id	AC2
Number of Residues	22
Details	BINDING SITE FOR RESIDUE LRY B 301

Chain	Residue
B	GLN14
B	ARG43
B	ILE64
B	TYR75
B	THR147
B	TYR151
B	GLU180
B	GLY181
B	ARG182
B	GLY203
B	GLY204
B	ARG208
B	HOH2030
B	HOH2033
B	HOH2161
B	HOH2165
B	HOH2185
B	HOH2186
B	HOH2202
B	HOH2210
B	HOH2222
B	HOH2223

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 1221

Chain	Residue
A	ARG208
A	PRO209
A	GLN210
A	HOH2069
A	HOH2070

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL B 1221

Chain	Residue
B	ARG208
B	PRO209
B	GLN210
B	HOH2045
B	HOH2049

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