4UTF

Structure of the GH99 endo-alpha-mannosidase from Bacteroides xylanisolvens in complex with mannose-alpha-1,3-isofagomine and alpha- 1,2-mannobiose

Summary for 4UTF

• Entry DOI: 10.2210/pdb4utf/pdb
• Related PRD ID: PRD_900111
• Descriptor: GLYCOSYL HYDROLASE FAMILY 71, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, alpha-D-mannopyranose, ... (6 entities in total)
• Functional Keywords: hydrolase, bacteroides, alpha-mannosidase, polysaccharide utilisation locus, mannose, mannan, biocatalysis, yeast, catalytic domain, carbohydrate conformation, cazy, glycoside hydrolase
• Biological source: BACTEROIDES XYLANISOLVENS
• Total number of polymer chains: 1
• Total formula weight: 44273.03

Authors

Cuskin, F.,Lowe, E.C.,Temple, M.J.,Zhu, Y.,Pudlo, N.A.,Cameron, E.A.,Urs, K.,Thompson, A.J.,Cartmell, A.,Rogowski, A.,Tolbert, T.,Piens, K.,Bracke, D.,Vervecken, W.,Hakki, Z.,Speciale, G.,Munoz-Munoz, J.L.,Pena, M.J.,McLean, R.,Suits, M.D.,Boraston, A.B.,Atherly, T.,Ziemer, C.J.,Williams, S.J.,Davies, G.J.,Abbott, D.W.,Martens, E.C.,Gilbert, H.J. (deposition date: 2014-07-21, release date: 2014-12-24, Last modification date: 2020-07-29)

• Primary citation: Cuskin, F.,Lowe, E.C.,Temple, M.,Zhu, Y.,Cameron, E.A.,Pudlo, N.A.,Porter, N.T.,Urs, K.,Thompson, A.J.,Cartmell, A.,Rogowski, A.,Hamilton, B.S.,Chen, R.,Tolbert, T.J.,Piens, K.,Bracke, D.,Vervecken, W.,Hakki, Z.,Speciale, G.,Munoz-Munoz, J.L.,Day, A.,Pena, M.J.,Mclean, R.,Suits, M.D.L.,Boraston, A.B.,Atherly, T.,Ziemer, C.J.,Williams, S.J.,Davies, G.J.,Abbott, W.D.,Martens, E.C.,Gilbert, H.J.; Human Gut Bacteroidetes Can Utilize Yeast Mannan Through a Selfish Mechanism.; Nature, 517:165-, 2015; PubMed: 25567280; DOI: 10.1038/NATURE13995

Experimental method

X-RAY DIFFRACTION (1.3 Å)