4UT6

Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 B7

4UT6 の概要

• エントリーDOI: 10.2210/pdb4ut6/pdb
• 関連するPDBエントリー: 4UT7 4UT8 4UT9
• 分子名称: ENVELOPE GLYCOPROTEIN E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2, ... (6 entities in total)
• 機能のキーワード: viral protein, membrane fusion, class 2 fusion protein, dengue antibody neutralization, immune system, immune system-viral protein complex
• 由来する生物種: DENGUE VIRUS 2; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 202422.84

構造登録者

Rouvinski, A.,Guardado-Calvo, P.,Barba-Spaeth, G.,Duquerroy, S.,Vaney, M.C.,Rey, F.A. (登録日: 2014-07-18, 公開日: 2015-01-28, 最終更新日: 2024-01-10)

• 主引用文献: Rouvinski, A.,Guardado-Calvo, P.,Barba-Spaeth, G.,Duquerroy, S.,Vaney, M.,Kikuti, C.M.,Sanchez, M.E.N.,Dejnirattisai, W.,Wongwiwat, W.,Haouz, A.,Girard-Blanc, C.,Petres, S.,Shepard, W.E.,Despres, P.,Arenzana-Seisdedos, F.,Dussart, P.,Mongkolsapaya, J.,Screaton, G.R.,Rey, F.A.; Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.; Nature, 520:109-, 2015; PubMed: 25581790; DOI: 10.1038/NATURE14130

実験手法

X-RAY DIFFRACTION (3.2 Å)