4USD
Human STK10 (LOK) with SB-633825
Summary for 4USD
Entry DOI | 10.2210/pdb4usd/pdb |
Related | 4USE 4USF |
Descriptor | SERINE/THREONINE-PROTEIN KINASE 10, 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl}pyridine (2 entities in total) |
Functional Keywords | transferase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 69564.37 |
Authors | Elkins, J.M.,Salah, E.,Szklarz, M.,von Delft, F.,Canning, P.,Raynor, J.,Bountra, C.,Edwards, A.M.,Knapp, S. (deposition date: 2014-07-07, release date: 2015-07-22, Last modification date: 2024-05-08) |
Primary citation | Elkins, J.M.,Fedele, V.,Szklarz, M.,Abdul Azeez, K.R.,Salah, E.,Mikolajczyk, J.,Romanov, S.,Sepetov, N.,Huang, X.P.,Roth, B.L.,Al Haj Zen, A.,Fourches, D.,Muratov, E.,Tropsha, A.,Morris, J.,Teicher, B.A.,Kunkel, M.,Polley, E.,Lackey, K.E.,Atkinson, F.L.,Overington, J.P.,Bamborough, P.,Moller, S.,Price, D.J.,Willson, T.M.,Drewry, D.H.,Knapp, S.,Zuercher, W.J. Comprehensive Characterization of the Published Kinase Inhibitor Set. Nat.Biotechnol., 34:95-, 2016 Cited by PubMed: 26501955DOI: 10.1038/NBT.3374 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.05 Å) |
Structure validation
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