4UHX
Human aldehyde oxidase in complex with phthalazine and thioridazine
Summary for 4UHX
Entry DOI | 10.2210/pdb4uhx/pdb |
Related | 4UHW |
Descriptor | ALDEHYDE OXIDASE, FE2/S2 (INORGANIC) CLUSTER, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ... (10 entities in total) |
Functional Keywords | oxidoreductase, aldehyde oxidase, drug metabolism, molybdenum enzymes, xanthine oxidase, phthalazine, thioridazine |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm : Q06278 |
Total number of polymer chains | 1 |
Total formula weight | 150865.44 |
Authors | Coelho, C.,Romao, M.J.,Santos-Silva, T. (deposition date: 2015-03-26, release date: 2015-09-02, Last modification date: 2024-01-10) |
Primary citation | Coelho, C.,Foti, A.,Hartmann, T.,Santos-Silva, T.,Leimkuhler, S.,Romao, M.J. Structural Insights Into Xenobiotic and Inhibitor Binding to Human Aldehyde Oxidase Nat.Chem.Biol., 11:779-, 2015 Cited by PubMed: 26322824DOI: 10.1038/NCHEMBIO.1895 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report