4UE0

Structure of the bovine atadenovirus type 4 fibre head protein

4UE0 の概要

• エントリーDOI: 10.2210/pdb4ue0/pdb
• 分子名称: FIBER, CARBONATE ION, THIOCYANATE ION, ... (4 entities in total)
• 機能のキーワード: viral protein
• 由来する生物種: BOVINE ADENOVIRUS 4
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 40802.50

構造登録者

Nguyen, T.H.,van Raaij, M.J. (登録日: 2014-12-14, 公開日: 2015-06-03, 最終更新日: 2024-05-08)

主引用文献

Nguyen, T.H.,Vidovszky, M.Z.,Ballmann, M.Z.,Sanz-Gaitero, M.,Singh, A.K.,Harrach, B.,Benko, M.,van Raaij, M.J.
Crystal structure of the fibre head domain of bovine adenovirus 4, a ruminant atadenovirus.
Virol. J., 12:81-81, 2015

PubMed Abstract: In adenoviruses, primary host cell recognition is generally performed by the head domains of their homo-trimeric fibre proteins. This first interaction is reversible. A secondary, irreversible interaction subsequently takes place via other adenovirus capsid proteins and leads to a productive infection. Although many fibre head structures are known for human mastadenoviruses, not many animal adenovirus fibre head structures have been determined, especially not from those belonging to adenovirus genera other than Mastadenovirus.

PubMed: 25994880
DOI: 10.1186/s12985-015-0309-1

実験手法

X-RAY DIFFRACTION (1.17 Å)