4UBU
Structure of a modified C93S variant of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis in complex with CoA
Summary for 4UBU
Entry DOI | 10.2210/pdb4ubu/pdb |
Descriptor | Acetyl-CoA acetyltransferase FadA5, COENZYME A, GLYCEROL, ... (4 entities in total) |
Functional Keywords | acetylated, degradative thiolase, transferase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 8 |
Total formula weight | 345490.21 |
Authors | Schaefer, C.M.,Kisker, C. (deposition date: 2014-08-13, release date: 2014-12-17, Last modification date: 2023-12-20) |
Primary citation | Schaefer, C.M.,Lu, R.,Nesbitt, N.M.,Schiebel, J.,Sampson, N.S.,Kisker, C. FadA5 a Thiolase from Mycobacterium tuberculosis: A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis. Structure, 23:21-33, 2015 Cited by PubMed: 25482540DOI: 10.1016/j.str.2014.10.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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