4UAI

Crystal structure of CXCL12 in complex with inhibitor

4UAI の概要

• エントリーDOI: 10.2210/pdb4uai/pdb
• 分子名称: Stromal cell-derived factor 1, 1-phenyl-3-[4-(1H-tetrazol-5-yl)phenyl]urea, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: cxcl12, inhibitor, complex, chemokine, cytokine-cytokine inhibitor complex, cytokine/cytokine inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 16429.33

構造登録者

Smith, E.W.,Chen, Y. (登録日: 2014-08-09, 公開日: 2014-11-12, 最終更新日: 2023-09-27)

• 主引用文献: Smith, E.W.,Liu, Y.,Getschman, A.E.,Peterson, F.C.,Ziarek, J.J.,Li, R.,Volkman, B.F.,Chen, Y.; Structural Analysis of a Novel Small Molecule Ligand Bound to the CXCL12 Chemokine.; J.Med.Chem., 57:9693-9699, 2014; PubMed: 25356720; DOI: 10.1021/jm501194p

実験手法

X-RAY DIFFRACTION (1.9 Å)