4UAB

Crystal structure of a TRAP periplasmic solute binding protein from Chromohalobacter salexigens DSM 3043 (Csal_0678), Target EFI-501078, with bound ethanolamine

Replaces:  4N5W

Summary for 4UAB

• Entry DOI: 10.2210/pdb4uab/pdb
• Descriptor: Twin-arginine translocation pathway signal, CHLORIDE ION, ETHANOLAMINE, ... (4 entities in total)
• Functional Keywords: trap periplasmic solute binding family, enzyme function initiative, efi, structural genomics, transport protein
• Biological source: Chromohalobacter salexigens
• Total number of polymer chains: 2
• Total formula weight: 80495.03

Authors

Vetting, M.W.,Al Obaidi, N.F.,Morisco, L.L.,Wasserman, S.R.,Sojitra, S.,Stead, M.,Attonito, J.D.,Scott Glenn, A.,Chowdhury, S.,Evans, B.,Hillerich, B.,Love, J.,Seidel, R.D.,Imker, H.J.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (deposition date: 2014-08-08, release date: 2014-09-03, Last modification date: 2023-11-15)

• Primary citation: Vetting, M.W.,Al-Obaidi, N.,Zhao, S.,San Francisco, B.,Kim, J.,Wichelecki, D.J.,Bouvier, J.T.,Solbiati, J.O.,Vu, H.,Zhang, X.,Rodionov, D.A.,Love, J.D.,Hillerich, B.S.,Seidel, R.D.,Quinn, R.J.,Osterman, A.L.,Cronan, J.E.,Jacobson, M.P.,Gerlt, J.A.,Almo, S.C.; Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.; Biochemistry, 54:909-931, 2015; PubMed: 25540822; DOI: 10.1021/bi501388y

Experimental method

X-RAY DIFFRACTION (1.4 Å)