4U6E
HsMetAP in complex with (amino(phenyl)methyl)phosphonic acid
Summary for 4U6E
| Entry DOI | 10.2210/pdb4u6e/pdb |
| Related | 4U1B 4U69 4U6C 4u6j 4u6w 4u6z 4u70 4u71 4u73 4u75 4u76 |
| Descriptor | Methionine aminopeptidase 1, COBALT (II) ION, [(R)-amino(phenyl)methyl]phosphonic acid, ... (4 entities in total) |
| Functional Keywords | hydrolase, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 34759.21 |
| Authors | Arya, T.,Addlagatta, A. (deposition date: 2014-07-28, release date: 2015-03-25, Last modification date: 2024-03-20) |
| Primary citation | Arya, T.,Reddi, R.,Kishor, C.,Ganji, R.J.,Bhukya, S.,Gumpena, R.,McGowan, S.,Drag, M.,Addlagatta, A. Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases J.Med.Chem., 58:2350-2357, 2015 Cited by PubMed: 25699713DOI: 10.1021/jm501790e PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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