4U1G

Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody QA1

4U1G の概要

• エントリーDOI: 10.2210/pdb4u1g/pdb
• 分子名称: Reticulocyte binding protein 5, QA1 monoclonal antibody heavy chain, QA1 monoclonal antibody light chain (3 entities in total)
• 機能のキーワード: malaria erythrocyte invasion antibody-mediated inhibition, immune system
• 由来する生物種: Plasmodium falciparum; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 234412.56

構造登録者

Wright, K.E.,Hjerrild, K.A.,Bartlett, J.,Douglas, A.D.,Jin, J.,Brown, R.E.,Ashfield, R.,Clemmensen, S.B.,de Jongh, W.A.,Draper, S.J.,Higgins, M.K. (登録日: 2014-07-15, 公開日: 2014-08-13, 最終更新日: 2023-12-20)

• 主引用文献: Wright, K.E.,Hjerrild, K.A.,Bartlett, J.,Douglas, A.D.,Jin, J.,Brown, R.E.,Illingworth, J.J.,Ashfield, R.,Clemmensen, S.B.,de Jongh, W.A.,Draper, S.J.,Higgins, M.K.; Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.; Nature, 515:427-430, 2014; PubMed: 25132548; DOI: 10.1038/nature13715

実験手法

X-RAY DIFFRACTION (3.1 Å)