4U15
M3-mT4L receptor bound to tiotropium
Summary for 4U15
Entry DOI | 10.2210/pdb4u15/pdb |
Related | 4U14 4U16 |
Descriptor | Muscarinic acetylcholine receptor M3,Lysozyme,Muscarinic acetylcholine receptor M3, (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane, HEXAETHYLENE GLYCOL, ... (6 entities in total) |
Functional Keywords | gpcr t4l stabillized crystallography, membrane protein, membrane protein-inhibitor complex, membrane protein/inhibitor |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P08483 |
Total number of polymer chains | 2 |
Total formula weight | 98943.82 |
Authors | Thorsen, T.S.,Matt, R.,Weis, W.I.,Kobilka, B. (deposition date: 2014-07-15, release date: 2014-11-26, Last modification date: 2023-12-27) |
Primary citation | Thorsen, T.S.,Matt, R.,Weis, W.I.,Kobilka, B.K. Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis. Structure, 22:1657-1664, 2014 Cited by PubMed: 25450769DOI: 10.1016/j.str.2014.08.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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