4TWK
Crystal structure of human two pore domain potassium ion channel TREK1 (K2P2.1)
Summary for 4TWK
Entry DOI | 10.2210/pdb4twk/pdb |
Descriptor | Potassium channel subfamily K member 2, POTASSIUM ION, Octyl Glucose Neopentyl Glycol, ... (6 entities in total) |
Functional Keywords | ion channel, membrane protein, k2p, transport protein |
Biological source | Homo sapiens (Human) |
Cellular location | Isoform 1: Cell membrane; Multi-pass membrane protein (By similarity). Isoform 2: Cell membrane; Multi-pass membrane protein (By similarity). Isoform 4: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity): O95069 |
Total number of polymer chains | 2 |
Total formula weight | 65665.15 |
Authors | Pike, A.C.W.,Dong, Y.Y.,Tessitore, A.,Goubin, S.,Strain-Damerell, C.,Mukhopadhyay, S.,Kupinska, K.,Wang, D.,Chalk, R.,Berridge, G.,Grieben, M.,Shrestha, L.,Ang, J.H.,Mackenzie, A.,Quigley, A.,Bushell, S.R.,Shintre, C.A.,Faust, B.,Chu, A.,Dong, L.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Burgess-Brown, N.A.,Carpenter, E.P. (deposition date: 2014-06-30, release date: 2014-08-06, Last modification date: 2023-12-20) |
Primary citation | Pike, A.C.W.,Dong, Y.Y.,Tessitore, A.,Goubin, S.,Strain-Damerell, C.,Mukhopadhyay, S.,Kupinska, K.,Wang, D.,Chalk, R.,Berridge, G.,Grieben, M.,Shrestha, L.,Ang, J.H.,Mackenzie, A.,Quigley, A.,Bushell, S.R.,Shintre, C.A.,Faust, B.,Chu, A.,Dong, L.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Burgess-Brown, N.A.,Carpenter, E.P. Crystal structure of human two pore domain potassium ion channel TREK1 (K2P2.1) To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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