4TWK

Crystal structure of human two pore domain potassium ion channel TREK1 (K2P2.1)

4TWK の概要

• エントリーDOI: 10.2210/pdb4twk/pdb
• 分子名称: Potassium channel subfamily K member 2, POTASSIUM ION, Octyl Glucose Neopentyl Glycol, ... (6 entities in total)
• 機能のキーワード: ion channel, membrane protein, k2p, transport protein
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Isoform 1: Cell membrane; Multi-pass membrane protein (By similarity). Isoform 2: Cell membrane; Multi-pass membrane protein (By similarity). Isoform 4: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity): O95069
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65665.15

構造登録者

Pike, A.C.W.,Dong, Y.Y.,Tessitore, A.,Goubin, S.,Strain-Damerell, C.,Mukhopadhyay, S.,Kupinska, K.,Wang, D.,Chalk, R.,Berridge, G.,Grieben, M.,Shrestha, L.,Ang, J.H.,Mackenzie, A.,Quigley, A.,Bushell, S.R.,Shintre, C.A.,Faust, B.,Chu, A.,Dong, L.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Burgess-Brown, N.A.,Carpenter, E.P. (登録日: 2014-06-30, 公開日: 2014-08-06, 最終更新日: 2023-12-20)

• 主引用文献: Pike, A.C.W.,Dong, Y.Y.,Tessitore, A.,Goubin, S.,Strain-Damerell, C.,Mukhopadhyay, S.,Kupinska, K.,Wang, D.,Chalk, R.,Berridge, G.,Grieben, M.,Shrestha, L.,Ang, J.H.,Mackenzie, A.,Quigley, A.,Bushell, S.R.,Shintre, C.A.,Faust, B.,Chu, A.,Dong, L.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Burgess-Brown, N.A.,Carpenter, E.P.; Crystal structure of human two pore domain potassium ion channel TREK1 (K2P2.1); To Be Published,

実験手法

X-RAY DIFFRACTION (2.6 Å)