4TWC
2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4- carboxamide derivatives as potent inhibitors of CK1d/e
Summary for 4TWC
Entry DOI | 10.2210/pdb4twc/pdb |
Descriptor | Casein kinase I isoform delta, SULFATE ION, GLYCEROL, ... (7 entities in total) |
Functional Keywords | ck1d, ck1e, phosphorylation, small molecule inhibitor, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 71359.66 |
Authors | Bischof, J.,Leban, L.,Zaja, M.,Grothey, A.,Radunsky, B.,Othersen, O.,Strobl, S.,Vitt, D.,Knippschild, U. (deposition date: 2014-06-30, release date: 2014-10-08, Last modification date: 2023-12-20) |
Primary citation | Bischof, J.,Leban, J.,Zaja, M.,Grothey, A.,Radunsky, B.,Othersen, O.,Strobl, S.,Vitt, D.,Knippschild, U. 2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1d/e. Amino Acids, 43:1577-1591, 2012 Cited by PubMed: 22331384DOI: 10.1007/s00726-012-1234-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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