4TVA

Universal Pathway for Post-Transfer Editing Reactions: Insight from Crystal structure of TthPheRS with Puromycine

Summary for 4TVA

Entry DOI	10.2210/pdb4tva/pdb
Related	3HFZ
Descriptor	Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, PHENYLALANINE, ... (5 entities in total)
Functional Keywords	puromycine, editing, trna, phers, ligase-antibiotic complex, ligase/antibiotic
Biological source	Thermus thermophilus More
Cellular location	Cytoplasm: P27001 P27002
Total number of polymer chains	2
Total formula weight	126666.55
Authors	Safro, M.,Klipcan, L.,Tworowski, D.,Peretz, M. (deposition date: 2014-06-26, release date: 2015-03-18, Last modification date: 2023-09-27)
Primary citation	Tworowski, D.,Klipcan, L.,Peretz, M.,Moor, N.,Safro, M.G. Universal pathway for posttransfer editing reactions: Insights from the crystal structure of TtPheRS with puromycin. Proc.Natl.Acad.Sci.USA, 112:3967-3972, 2015 Cited by PubMed: 25775602 DOI: 10.1073/pnas.1414852112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.597 Å)

Structure validation