4TR3
Mouse iodothyronine deiodinase 3 catalytic core, SeMet-labeled active site mutant SeCys->Cys
Summary for 4TR3
| Entry DOI | 10.2210/pdb4tr3/pdb |
| Descriptor | Type III iodothyronine deiodinase (2 entities in total) |
| Functional Keywords | deiodinase, thyronine hormones, thioredoxin fold, oxidoreductase |
| Biological source | Mus musculus (House mouse) |
| Cellular location | Cell membrane ; Single-pass type II membrane protein : Q91ZI8 |
| Total number of polymer chains | 1 |
| Total formula weight | 21696.64 |
| Authors | Steegborn, C.,Schweizer, U.,Schlicker, C. (deposition date: 2014-06-13, release date: 2014-07-23, Last modification date: 2015-02-04) |
| Primary citation | Schweizer, U.,Schlicker, C.,Braun, D.,Kohrle, J.,Steegborn, C. Crystal structure of mammalian selenocysteine-dependent iodothyronine deiodinase suggests a peroxiredoxin-like catalytic mechanism. Proc.Natl.Acad.Sci.USA, 111:10526-, 2014 Cited by PubMed: 25002520DOI: 10.1073/pnas.1323873111 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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