4TQD
Crystal Structure of the C-terminal domain of IFRS bound with 3-iodo-L-Phe and ATP
Summary for 4TQD
Entry DOI | 10.2210/pdb4tqd/pdb |
Descriptor | Pyrrolysine--tRNA ligase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | amino acyl-trna synthetases, archaeal proteins, evolution, molecular, genetic code, substrate specificity, ligase |
Biological source | Methanosarcina mazei |
Cellular location | Cytoplasm : Q8PWY1 |
Total number of polymer chains | 1 |
Total formula weight | 34704.88 |
Authors | Nakamura, A.,O'Donoghue, P.,Soll, D. (deposition date: 2014-06-11, release date: 2014-11-12, Last modification date: 2023-11-15) |
Primary citation | Guo, L.T.,Wang, Y.S.,Nakamura, A.,Eiler, D.,Kavran, J.M.,Wong, M.,Kiessling, L.L.,Steitz, T.A.,O'Donoghue, P.,Soll, D. Polyspecific pyrrolysyl-tRNA synthetases from directed evolution. Proc.Natl.Acad.Sci.USA, 111:16724-16729, 2014 Cited by PubMed: 25385624DOI: 10.1073/pnas.1419737111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1429 Å) |
Structure validation
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