4TNV

C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab in a non-conducting conformation

4TNV の概要

• エントリーDOI: 10.2210/pdb4tnv/pdb
• 関連するPDBエントリー: 3RHW 3RI5 3RIA 3RIF 4TNW
• 分子名称: Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, Mouse monoclonal Fab fragment, heavy chain, Mouse monoclonal Fab fragment, light chain, ... (7 entities in total)
• 機能のキーワード: membrane protein, ligand-gated ion channel, neurotransmitter receptor, cys-loop receptor, transport protein-immune system complex, transport protein/immune system
• 由来する生物種: Caenorhabditis elegans; 詳細
• タンパク質・核酸の鎖数: 30
• 化学式量合計: 878622.71

構造登録者

Althoff, T.,Hibbs, R.E.,Banerjee, S.,Gouaux, E. (登録日: 2014-06-05, 公開日: 2014-08-13, 最終更新日: 2023-09-27)

• 主引用文献: Althoff, T.,Hibbs, R.E.,Banerjee, S.,Gouaux, E.; X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.; Nature, 512:333-337, 2014; PubMed: 25143115; DOI: 10.1038/nature13669

実験手法

X-RAY DIFFRACTION (3.6 Å)