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4TNQ

Structural basis of cellular dNTP regulation, SAMHD1-GTP-dTTP-dTTP complex

Summary for 4TNQ
Entry DOI10.2210/pdb4tnq/pdb
Related4TNP 4TNR 4TNX 4TNY 4TNZ 4TO0 4TO1 4TO2 4TO3 4TO4 4TO5 4TO6
DescriptorDeoxynucleoside triphosphate triphosphohydrolase SAMHD1, THYMIDINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywordssamhd1, hiv, restriction factor, dntpase, dntp regulation, host pathogen interaction, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : Q9Y3Z3
Total number of polymer chains4
Total formula weight244463.97
Authors
Ji, X.,Tang, C.,Zhao, Q.,Wang, W.,Xiong, Y. (deposition date: 2014-06-04, release date: 2014-10-01, Last modification date: 2023-09-27)
Primary citationJi, X.,Tang, C.,Zhao, Q.,Wang, W.,Xiong, Y.
Structural basis of cellular dNTP regulation by SAMHD1.
Proc.Natl.Acad.Sci.USA, 111:E4305-E4314, 2014
Cited by
PubMed: 25267621
DOI: 10.1073/pnas.1412289111
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.55 Å)
Structure validation

217705

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